Alcohols and polyols

Organic compounds containing one or more hydroxyl functional groups bonded to a carbon atom; hydroxyls consist of an oxygen atom bonded to a hydrogen atom. Alcohols exist in chain, or as closed rings. Polyols contain two or more hydroxyl groups.

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2,251 – 2,265 of 6,680 results

2,251

Medchemexpress LLC Naluzotan hydrochlo | 5MG

Naluzotan hydrochlo | 5MG

Pricing & Availability

2,252

Medchemexpress LLC VTP-27999 Hydrochloride | 1264191-73-2 | 98.2% | C26H42Cl2N4O5 | 10MM/1ML

VTP-27999 Hcl is an alkyl amine Renin inhibitor that is useful for Hypertension and End-Organ Diseases. Its IC50 value targets Renin.

Molecular weight: 561.54
Appearance: Solid
Color: White to yellow
Solubility in water: ≥ 100 mg/mL (178.08 mM)
Storage as solid: 4°C, sealed, away from moisture
Storage in solvent: -80°C for 6 months; -20°C for 1 month (sealed, away from moisture)

Pricing & Availability

2,253

Medchemexpress LLC Dopexamine hydrochloride | 86484-91-5 | 429.42 | 10 MG

Dopexamine hydrochloride | 86484-91-5 | 429.42 | 10 MG

Pricing & Availability

2,254

Medchemexpress LLC Alpelisib (hydrochloride) | 1584128-91-5 | C19H23ClF3N5O2S | 100 MG

Alpelisib hydrochloride is a potent, orally active, and selective PI3Kα inhibitor with demonstrated antineoplastic activity. It potently inhibits Akt phosphorylation in cells transformed with PI3Kα and also exhibits reduced inhibitory activity in PI3Kβ or PI3Kδ isoforms transformed cells.

Potently inhibits common PIK3CA somatic mutations (H1047R, E545K)
Significantly reduces tumor volumes and ectopic bone matrix deposition in vivo
Induces cell cycle arrest in the G0/G1 phase of human and murine osteosarcoma cell lines
Used in various clinical trials for diverse conditions and phases

Pricing & Availability

2,255

Medchemexpress LLC Aprindine hydrochloride | 33237-74-0 | 99.0% | 358.95 g·mol⁻¹ | C22H31ClN2 | 10 MG

Aprindine hydrochloride is a class I-b anti-arrhythmic research compound that blocks sodium channels (INa) and is used to study cardiac electrophysiology. Supplied as the hydrochloride salt in small milligram quantities, it is intended for analytical and preclinical research applications.

Class I-b anti-arrhythmic agent; sodium channel blocker.
Hydrochloride salt form for improved solubility.
Available in small, precise milligram pack sizes.
High purity suitable for analytical and preclinical studies.
Used in electrophysiology and cardiovascular research applications.

Pricing & Availability

2,256

Medchemexpress LLC Eperisone (hydrochloride) | 56839-43-1 | 99.95% | 25 MG

Eperisone Hydrochloride is an orally active antispastic agent that also exhibits a vasodilator effect. It is used in research for muscle stiffness and pain. This compound is a potent and selective P2X7 receptor antagonist and also shows antagonism for human P2X3. Eperisone Hydrochloride functions by relaxing both skeletal and vascular smooth muscles, leading to various effects such as reduced myotonia, improved circulation, and suppression of the pain reflex.

Antispastic agent
Vasodilator effect
P2X7 receptor antagonist
P2X3 antagonist
Muscle relaxation
Therapeutic effects
Research use only

Pricing & Availability

2,257

Medchemexpress LLC Alfuzosin (hydrochloride) | 81403-68-1 | 99.7% | 25 MG

Alfuzosin hydrochloride is an orally active, selective, and competitive α1-adrenoceptor antagonist. It relaxes the muscles of the prostate and bladder neck, aiding in urination. This compound is used in the study of benign prostatic hyperplasia (BPH).

Orally active compound
Selective and competitive α1-adrenoceptor antagonist
Relaxes prostate and bladder neck muscles
Aids in urination
Used for benign prostatic hyperplasia (BPH) studies

Pricing & Availability

2,258

Medchemexpress LLC Alectinib hydrochloride | 1256589-74-8 | 99.9% | 25 MG

Alectinib hydrochloride is a potent, selective, and orally available ALK inhibitor. It demonstrates effective central nervous system (CNS) penetration.

Potent and selective ALK inhibitor
Orally available
Inhibits ALK F1174L and ALK R1275Q
Effective central nervous system (CNS) penetration
Reduces cell activity in a dose-dependent manner
Leads to dose-dependent tumor growth inhibition and regression

Pricing & Availability

2,259

Medchemexpress LLC AR-R17779 hydrochloride | 178419-42-6 | MFCD20926337 | 99.0% | 218.68 | C9H15ClN2O2 | 5 MG

AR-R17779 hydrochloride is a selective agonist of α7 nicotinic acetylcholine receptors supplied as the hydrochloride salt for laboratory research. It has been reported to influence learning and memory, show anxiolytic activity, and modulate anti-inflammatory cholinergic pathways. Purity is typically 99.0%.

Selective α7 nicotinic receptor agonist.
Provided as the hydrochloride salt.
Used in neuroscience and pharmacology research.
Reported effects on learning, memory, anxiety, and inflammation pathways.
High purity (99.0%).
Molecular weight 218.68; formula C9H15ClN2O2.
Available in small pack sizes for laboratory use.

Pricing & Availability

2,260

Medchemexpress LLC Iptacopan (hydrochloride) | 1646321-63-2 | 99.83% | 25 MG

Iptacopan (LNP023) hydrochloride is an effective, orally-active, and highly selective factor B inhibitor. With an IC50 of 10 nM and a KD of 7.9 nM, it exerts a proximal effect in the complement cascade reaction, preventing the destruction of red blood cells in PNH and damage to renal cells in IgAN and C3G. It is used for studying complement-mediated diseases, including paroxysmal nocturnal hemoglobinuria (PNH), primary immunoglobulin A nephropathy (IgAN), and complement 3 glomerulopathy (C3G).

Highly selective factor B inhibitor.
Orally active.
Potent inhibition of alternative complement pathway (AP)-induced membrane attack complex (MAC) formation.
Excellent selectivity over other proteases.
Prevents destruction of red blood cells in PNH.
Prevents damage to renal cells in IgAN and C3G.
Used for studying complement-mediated diseases.

Pricing & Availability

2,261

Medchemexpress LLC SCH-23390 hydrochloride | 125941-87-9 | 99.8% | 324.24 | 1 ML

SCH-23390 hydrochloride is a potent and selective dopamine D1-like receptor antagonist with Kis of 0.2 nM and 0.3 nM for the D1 and D5 receptor, respectively. It is also a potent and high efficacy human 5-HT2C receptor agonist with a Ki of 9.3 nM, and binds with high affinity to 5-HT2 and 5-HT1C receptors. It inhibits G protein-coupled inwardly rectifying potassium (GIRK) channels with an IC50 of 268 nM. For research use only.

Potent and selective dopamine D1-like receptor antagonist.
Potent and high efficacy human 5-HT2C receptor agonist.
Binds with high affinity to 5-HT2 and 5-HT1C receptors.
Inhibits G protein-coupled inwardly rectifying potassium (GIRK) channels.
Used in studies of neurological disorders like psychosis and Parkinson's disease.
Used in topographical determination of brain D1 receptors.

Pricing & Availability

2,262

Medchemexpress LLC Reserpine (hydrochloride) | 16994-56-2 | 645.14 | 1 ML

Reserpine (hydrochloride) | 16994-56-2 | 645.14 | 1 ML

Pricing & Availability

2,263

Medchemexpress LLC EPZ004777 hydrochloride | 1380316-03-9 | C28H42ClN7O4 | 50 MG

EPZ004777 hydrochloride is an effective and selective DOT1L inhibitor, reducing H3K79me2 and H3K79me1 levels and down-regulating HOXA9 and MEIS1 expression. This compound selectively inhibits the proliferation of MLL rearrangement cells, promoting their differentiation and apoptosis, making it useful for leukemia research.

Target: histone methyltransferase; apoptosis
Pathway: epigenetics; apoptosis
Potent and selective DOT1L inhibitor (IC50 of 0.4 nM)
Reduces H3K79me2 and H3K79me1 levels, down-regulating HOXA9 and MEIS1 expression
Selectively inhibits MLL rearrangement cells, promoting differentiation and apoptosis
Well tolerated in vivo with no overt toxicity observed

Pricing & Availability

2,264

Medchemexpress LLC Donepezil Hydrochloride | 120011-70-3 | 99.9% | 50 MG

Donepezil Hydrochloride (E2020) is a reversible, selective AChE inhibitor with an IC50 of 6.7 nM, showing high selectivity for AChE over BuChE. It exhibits a neuroprotective effect on Aβ42 neurotoxicity. In vivo, Donepezil treatment prevents the progression of scopolamine-induced memory impairment in mice, demonstrating its potential in neurodegenerative research.

Reversible, selective AChE inhibitor
IC50 of 6.7 nM for AChE activity
High selectivity for AChE over BuChE
Exhibits a neuroprotective effect on Aβ42 neurotoxicity
Enhances phosphorylation of Akt and GSK-3β
Reduces phosphorylation of tau and glycogen synthase
Increases cell viability in cortical neuronal cells
Prevents scopolamine-induced memory impairment in mice

Pricing & Availability

2,265

eMolecules 51285-26-8 | Picolinimidamide hydrochloride | Ambeed | MFCD00052271 | 157.600 | C6H8ClN3 | 97.000 | Cl.NC(=N)c1ccccn1 | 10g | 490512023

Picolinimidamide hydrochloride | Ambeed | 51285-26-8 | MFCD00052271 | 157.600 | C6H8ClN3 | 97.000 | Cl.NC(=N)c1ccccn1 | 10g | 490512023

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Alcohols and polyols

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Medchemexpress LLC Naluzotan hydrochlo | 5MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC VTP-27999 Hydrochloride | 1264191-73-2 | 98.2% | C26H42Cl2N4O5 | 10MM/1ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Dopexamine hydrochloride | 86484-91-5 | 429.42 | 10 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Alpelisib (hydrochloride) | 1584128-91-5 | C19H23ClF3N5O2S | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Aprindine hydrochloride | 33237-74-0 | 99.0% | 358.95 g·mol⁻¹ | C22H31ClN2 | 10 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Eperisone (hydrochloride) | 56839-43-1 | 99.95% | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Alfuzosin (hydrochloride) | 81403-68-1 | 99.7% | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Alectinib hydrochloride | 1256589-74-8 | 99.9% | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC AR-R17779 hydrochloride | 178419-42-6 | MFCD20926337 | 99.0% | 218.68 | C9H15ClN2O2 | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Iptacopan (hydrochloride) | 1646321-63-2 | 99.83% | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC SCH-23390 hydrochloride | 125941-87-9 | 99.8% | 324.24 | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Reserpine (hydrochloride) | 16994-56-2 | 645.14 | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC EPZ004777 hydrochloride | 1380316-03-9 | C28H42ClN7O4 | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Donepezil Hydrochloride | 120011-70-3 | 99.9% | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More